Rudyk, Rafał ; Malinowski, Marek ; Mackiewicz, Agnieszka ; Będziński, Romuald ; Noszczyk-Nowak, Agnieszka ; Skonieczna, Joanna ; Madej, Jan
Pathological conditions of a male urethra, including fibrosis, have a mechanical background along the entire length of the urethra. They may be caused by excessive deformation of the urethra locally or globally. The condition of prolonged overload causes abnormal tissue remodelling and, consequently, the formation of a thick layer of scar tissue differentiated from the connective tissue of the urethra. ; This tissue, which has higher mechanical properties, is not highly deformable and therefore, causes a decrease in the diameter of the urethra, which results in conditions that disturb the natural flow of urine. In this paper, it was decided to determine the deformation conditions in the proximal part of the urethra. ; The study was conducted in three main stages. Transverse sections of the animal urethral tissues were prepared in order to examine mechanical properties and perform histological examinations. On the basis of these examinations, material models which fitted best for the experimental results were sought. ; Material constants of the Mooney-Rivlin material model with the best fit ratio were determined for further research. On the basis of histological photographs, a geometrical and numerical model of the urethra was developed. The urethra was tested in a flat state of deformation. The strain and stress fields of the Caucha tensor were examined. The methodology of testing the dynamics of the urine flow in the highly deformable urethra was proposed. This is important for the analysis of the influence of at excessive pressure on pathological tissue remodelling leading to fibrosis.
Zielona Góra: Uniwersytet Zielonogórski
JAME, volume 25, number 2 (2020)
Biblioteka Uniwersytetu Zielonogórskiego
Feb 23, 2023
Feb 23, 2023
|Numerical analysis of deformation and flow in the proximal area of the urethra||Feb 23, 2023|
Szafran, Jacek Juszczyk-Andraszyk, Klaudia Kamiński, Marcin Jurczak, Paweł - red.
Merah, Aissa Noureddine, Abdelkader Jurczak, Paweł - red.
Graba, Marcin Jurczak, Paweł - red.
Reddy, G. Jithender Raju, R. Srinivasa Rao, J. Anand Gorla, Rama Subba Reddy Jurczak, Paweł - red.
Prabhakar Reddy, Bijjula Jurczak, Paweł - red.
Grębowski, Karol Ulman, Zofia Jurczak, Paweł - red.
Srivastava, A.K.L. Pandey, S.R. Kumar, Ashwini Jurczak, Paweł - red.
Zielińska, Monika Jurczak, Paweł - red.